Excellent biodegradable and poor antigens properties enable collagen to be identified as an unrivalled natural material for medical applications. Therefore, collagen bio-materials can find a wide range of applications in vivo and in vitro.
Collagen is one of the most important components of the skin. It is highly preferred in tissue engineering applications because it does not lead to immunogenic reaction and is a relatively low cost material.
Collagen and gelatin are often preferred biomaterials in tissue engineering, and their properties can be listed as low cost, high biocompatibility, increasing cell adhesion, supporting cell proliferation, migration and differentiation.